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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIRREL All Species: 19.7
Human Site: S527 Identified Species: 43.33
UniProt: Q96J84 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96J84 NP_060710.3 757 83536 S527 L Y R R R K G S R K D V T L R
Chimpanzee Pan troglodytes XP_512603 643 68168 F414 S G T Q E S D F S R S F N C S
Rhesus Macaque Macaca mulatta XP_001116954 757 83517 S527 L Y R R R K G S R K D V T L R
Dog Lupus familis XP_545723 765 82684 S536 L Y R R R K G S R K D V T L R
Cat Felis silvestris
Mouse Mus musculus Q80W68 789 87158 S559 L Y R R R K G S R K D V T L R
Rat Rattus norvegicus Q6X936 789 87134 S559 L Y R R R K G S R K D V T L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519826 311 32978 I82 S A K P A A T I D W L R D G T
Chicken Gallus gallus XP_423078 443 49213 I214 Q A D A G Q Y I C K A I V P R
Frog Xenopus laevis NP_001079957 775 84238 V527 C R R P K K A V K D T Q I L A
Zebra Danio Brachydanio rerio NP_998033 807 87242 Q528 L V L F L Y R Q R K G S R R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q08180 764 82987 S530 L Q A K K S V S L L M T I V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.7 99.4 80.1 N.A. 91.7 91.2 N.A. 32.8 48.8 41 59.1 N.A. 27.6 N.A. N.A. N.A.
Protein Similarity: 100 46 99.8 84.9 N.A. 93.6 93.1 N.A. 36.3 52.8 55.3 72.1 N.A. 42.4 N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 13.3 20 20 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 6.6 26.6 33.3 20 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 10 10 10 10 0 0 0 10 0 0 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % C
% Asp: 0 0 10 0 0 0 10 0 10 10 46 0 10 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 10 0 0 0 10 0 0 0 % F
% Gly: 0 10 0 0 10 0 46 0 0 0 10 0 0 10 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 19 0 0 0 10 19 0 0 % I
% Lys: 0 0 10 10 19 55 0 0 10 64 0 0 0 0 0 % K
% Leu: 64 0 10 0 10 0 0 0 10 10 10 0 0 55 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 19 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 10 10 0 10 0 10 0 10 0 0 0 10 0 0 0 % Q
% Arg: 0 10 55 46 46 0 10 0 55 10 0 10 10 10 55 % R
% Ser: 19 0 0 0 0 19 0 55 10 0 10 10 0 0 10 % S
% Thr: 0 0 10 0 0 0 10 0 0 0 10 10 46 0 10 % T
% Val: 0 10 0 0 0 0 10 10 0 0 0 46 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 46 0 0 0 10 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _